… (AD) cell model and explored its potential signal transduction. Our results showed that
apigenin protected … neuronal viability and relieving mitochondrial membrane dissipation and …

… considerable potential anti-oxidant effects through their free … through attenuating p38
MAPK/JNK signaling during the … signaling of APPswe cells through inactivating p38 MAPK and …

… , preserving mitochondrial function, inhibiting p38 MAPK-MAPKAP kinase-… (A) Apigenin
treatment attenuates the learning deficits … It has been suggested that genetic inactivation of tumor …

… Apigenin is a potent antioxidant, anti-inflammatory, and anti-carcinogenic agent. Also, some
… of apigenin in Aβ 25–35-induced neurotoxicity and memory impairment in a rat model of AD. …

… -ERK1/2 from the cytoplasm to the nucleus was significantly … dose of Aβ via alteration of the
activation of the Ras-MAPK/ERK/CREB … quercetin, kaempferol and apigenin and their in vivo …

… double transgenic mouse model with apigenin during three months … are focused on attenuating
the amyloidogenic process, … the intraneuronal accumulation of β -amyloid in Alzheimer’s …

… by attenuating the expression of COX-2 and iNOS. At the … ROS generation; obstructing p38
MAPK, MAPKAP kinase-2, … in a copper-mediated β-amyloid neurotoxicity cell model of AD. …

… Apigenin attenuates coppermediated β-amyloid neurotoxicity through antioxidation,
mitochondrion protection and MAPK signal inactivation in an AD cell model. Brain Res. 2013; 1492: …

… , and then the p38 MAPK signaling pathway was activated, in … ], attenuating copper-mediated
β-amyloid neurotoxicity in an … via the release of Cyt-c from mitochondria into the cytoplasm …

… the mitochondrial release of ROS in β-amyloid peptides 25–… the GSK-3α isoform selective
inactivation that enhances the p-… of apigenin 50 µM (IC 50 value) can protect neurons against …